Cancer Weekly
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Astrocytoma
Investigators at Teikyo University target astrocytoma
May 5th, 2009
"Interferon beta 6 Million Units per week was administered to a patient with all aggressive astrocytoma in the tectum that was resistant to cisplatin, etoposide, vinblastine, and the oral alkylating agent temozolomide. The tumor was immunopositive for O-6-methylguanine-DNA methyltransferase (MGMT)," scientists writing in the journal Tumori report. "Interferon beta caused the disappearance of the gadolinium-enhanced lesion in the tectum. Interferons have apoptotic and antiangiogenic effects on tumor cells, and the lesion's disappearance may have been induced by complexes of these effects," wrote A. Matsuno and colleagues, Teikyo University. The...
Source: Cancer Weekly (2009-05-05)
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