Cancer Weekly
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Breast Cancer
Investigators at State University of New York have published new data on breast cancer
May 5th, 2009
"Phenethyl isothiocyanate (PEITC) and sulforaphane (SF) exhibit tumor preventive activity in lung, prostate, breast and colon cancers. Our objective was to examine the effect of these two isothiocyanates on estrogen receptor-related genes, and genes related to apoptosis and cell cycle in the estrogen-dependent breast cancer cell line MCF7 and in normal human epithelial breast (HME) cells," investigators in the United States report. "We treated cells with 0.3 mc M or 3.0 mc M concentrations of PEITC or SF. In HME cells, gene expression was significantly altered for 23 genes by PEITC at a concentration of 0.3 mc M and 4 genes at 3.0 mc M. SF altered the expression of 16...
Source: Cancer Weekly (2009-05-05)
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