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Monoclonal Antibodies

Research from V. Le Brun-Ly and co-researchers in the area of monoclonal antibodies described

Published in Cancer Weekly, May 5th, 2009

Scientists discuss in 'Cardiac toxicity with capecitabine, vinorelbine and trastuzumab therapy: case report and review of fluoropyrimidine-related cardiotoxicity' new findings in monoclonal antibodies. According to a study from Limoges, France, "A 45-year-old woman presented with a metastatic breast carcinoma and was treated with capecitabine, oral vinorelbine and trastuzumab combination therapy. The initial echocardiogram and the ECG were considered normal."

"She began treatment with 3-weekly cycles of the combination therapy. After the fourth dose of capecitabine, she presented with severe chest and arm pain, which was responsive to nitroglycerine spray. ECG at...

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