Pharmacokinetics
NKTR-105 Demonstrates Superior Antitumor Activity and Improved Pharmacokinetics Over Docetaxel in Preclinical Studies Presented at AACR
Published in Cancer Weekly, May 5th, 2009
In a comparative study of NKTR-105 and docetaxel, NKTR-105 treatment significantly delayed tumor growth as compared to docetaxel (122% v. 48%), which was associated with greater and sustained tumor exposure to docetaxel after NKTR-105 administration. Treatment with NKTR-105 increased docetaxel concentrations in tumors (0.4 to 4-fold...
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Source: Cancer Weekly (2009-05-05)
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