Glioblastoma
Research from R. Castriconi and co-authors provides new data about glioblastoma
Published in Cancer Weekly, May 12th, 2009
According to recent research published in the Journal of Immunology, "In this study, cancer cells were isolated from tumor specimens of nine glioblastoma patients. Glioblastoma cells, cultured under suitable culture conditions, displayed markers typical of neural stem cells, were capable of partial multilineage differentiation in vitro, and gave origin to infiltrating tumors when orthotopically injected in NOD/SCID mice."
"These cells, although resistant to freshly isolated NK cells, were highly susceptible to lysis mediated by both allogeneic and autologous IL-2 (or IL-15)-activated NK cells. Indeed, all stem cell-cultured glioblastoma cells analyzed did not...
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Source: Cancer Weekly (2009-05-12)
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