Lung Cancer

Findings from University of Munich provide new insights into lung cancer

Published in Cancer Weekly, May 12th, 2009

"Knowledge of differences in the cellular physiology of malignant and non-malignant cells is a prerequisite for the development of cancer treatments that effectively kill cancer without damaging normal cells. Calcium is a ubiquitous signal molecule that is involved in the control of proliferation and apoptosis," investigators in Munich, Germany report.

"We aimed to investigate if the endoplasmic reticulum (ER) Ca2+-homeostasis is different in lung cancer and normal human bronchial epithelial (NHBE) cells. The intracellular Ca2+-signaling was investigated using fluorescence microscopy and the expression of Ca2+-regulating proteins was assessed using Western Blot...

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Source: Cancer Weekly (2009-05-12)

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