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Cancer Gene Therapy
Recent studies from University of Toronto, Department of Medical Biophysics add new data to cancer gene therapy
May 19th, 2009
Research findings, 'The role of INI1/hSNF5 in gene regulation and cancer,' are discussed in a new report. According to a study from Toronto, Canada, "The precise modulation of chromatin dynamics is an essential and complex process that ensures the integrity of transcriptional regulation and prevents the transition of a normal cell into a cancerous one. ATP-dependent chromatin remodeling enzymes are multisubunit complexes that play a pivotal role in this operation through the mobilization of nucleosomes to promote DNA accessibility." "Chromatin remodeling is mediated by the interaction of DNA-binding factors and individual members of this complex, directing its targeted...
Source: Cancer Weekly (2009-05-19)
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