Cancer Weekly
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Adenovirus
Research on adenovirus detailed by scientists at Umea University
May 19th, 2009
According to recent research from Umea, Sweden, "Most adenoviruses bind directly to the coxsackie and adenovirus receptor (CAR) on target cells in vitro, but recent research has shown that adenoviruses can also use soluble components in body fluids for indirect binding to target cells. These mechanisms have been identified upon addressing the questions of how to de- and retarget adenovirus-based vectors for human gene and cancer therapy, but the newly identified mechanisms also suggest that the role of body fluids and their components may also be of importance for natural, primary infections." "Here we demonstrate that plasma, saliva, and tear fluid promote binding and...
Source: Cancer Weekly (2009-05-19)
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