Cancer Weekly
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Angiogenesis
Reports outline angiogenesis research from J.L. Yang and colleagues
May 19th, 2009
According to recent research from Changchun, People's Republic of China, "Basic fibroblast growth factor (bFGF) is closely involved in angiogenesis and tumor growth of various cancers, but its role in cervical cancer remains to be defined. We investigated the effects of bFGF on HeLa cell growth and studied its influence on the expression of angiogenin." "We transfected the bFGF gene in the sense and antisense orientation into HeLa cells, and obtained stable bFGF underexpressing and overexpressing transfectants. In our experiments, we demonstrated that inhibition of bFGF gene and protein expression in the bFGF antisense transfectants induced increased protein expression...
Source: Cancer Weekly (2009-05-19)
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