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Ovarian Cancer

New ovarian cancer research from University of Western Australia described

Published in Cancer Weekly, May 19th, 2009

"Serous ovarian cancer is the most prevalent type of ovarian cancer. The majority of women present at an advanced stage and patient survival is poor," researchers in Perth, Australia report.

"Resistance to chemotherapy is thought to relate to failure of tumours to undergo apoptosis. Secreted frizzled-related protein 4 (SFRP4) has been demonstrated to be involved in apoptosis in the ovary but not in ovarian tumours as yet. This study examined SFRP4 expression in ovarian cancers and Correlated this with expression of P-catenin, a main component of the WNT-Signalling pathway it inhibits. We examined 153 primary serous ovarian carcinomas for SFRP4 and B-catenin expression...

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