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Spectroscopy

Recent studies by J. Griffitts and co-authors add new data to spectroscopy findings

Published in Cancer Weekly, May 19th, 2009

"Current detection methods (computed tomography, ultrasound, and MRI) for hepatocarcinogenesis in humans rely on visual confirmation of neoplastic formations. A more effective early detection method is needed," scientists in the United States report.

"Using in vivo magnetic resonance spectroscopy (MRS), we show that alterations in the integral ratios of the bis-allyl to vinyl hydrogen protons in unsaturated lipid fatty acyl groups correlate with the development of neoplastic formations in vivo in a TGF alpha/c-myc mouse hepatocellular carcinoma (HCC) model. HPLC analysis of the TGF alpha/c-myc mice liver tissue revealed a significant increase in the amount of oleic...

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