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Cancer Weekly

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Biochemistry



New biochemistry study findings recently were reported by researchers at Environmental Protection Agency



May 19th, 2009

"Metabolomics is a technology for identifying and quantifying numerous biochemicals across metabolic pathways. Using this approach, we explored changes in biochemical profiles of human alveolar epithelial carcinoma (A549) cells following in vitro exposure to mainstream whole smoke (WS) aerosol as well as to wet total particulate matter (WTPM) or gas/vapor phase (GVP), the two constituent phases of WS from 2R4F Kentucky reference cigarettes," scientists in the United States report.

"A549 cells were exposed to WTPM or GVP (expressed as WTPM mass equivalent GVP volumes) at 0, 5, 25, or 50 mu g/mL or to WS from zero, two, four, and six cigarettes for 1 or 24 h. Cell pellets...


Source: Cancer Weekly (2009-05-19)

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