Glioma Therapy
Studies from Shandong University have provided new data on glioma therapy
Published in Cancer Weekly, May 19th, 2009
Data detailed in 'Tetrazolium violet induces apoptosis via caspases-8, -9 activation and Fas/FasL up-regulation in Rat C6 glioma cells' have been presented. "Tetrazolium violet (TV), a tetrazolium salt, was synthesized as a novel and potent anticancer agent with a broad spectrum of anticancer activity against many cancer cells. A previous study showed that tetrazolium violet inhibited cell growth, and induced cell cycle arrest and apoptosis in C6 Rat glioma cells," investigators in Jinan, People's Republic of China report.
"It also showed that treatment of cells with TV for 24 h resulted in a dramatic up-regulation of p53, and an increase in the activity of caspase-3,...
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Source: Cancer Weekly (2009-05-19)
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