Cancer Weekly
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Cancer Gene Therapy
New cancer gene therapy study findings have been published by E. Fattori and colleagues
May 19th, 2009
According to recent research published in the journal Human Gene Therapy, "Aberrant Her2/neu expression is associated with the development of epithelial-derived human carcinomas and for this reason it is considered a good target for immunologic intervention. To define methods to circumvent immunologic tolerance and to elicit immunity against the Her2/neu tumor-associated antigen in a suitable animal model, we have isolated the cDNA encoding the rhesus monkey homolog of human Her2/neu (RhErbB2) to construct DNA plasmids and adenoviral vectors for the development of a cancer vaccine against this protein." "To further increase the immunogenic potency of these...
Source: Cancer Weekly (2009-05-19)
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