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Cancer Weekly

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Cancer Gene Therapy



Studies from Chonnam National University, Medical Department have provided new information about cancer gene therapy



May 19th, 2009

According to recent research from South Korea, "Osteocalcin expression is restricted to osteoblasts and serum osteocalcin level is elevated in metastatic bone tumors including prostate tumours, which predominantly metastasizes to the bone and causes typical osteoblastic lesions. Previously, we have reported that osteocalcin RNA is widely expressed but incompletely spliced in the prostate including prostate tumors."

"Considering that many studies using osteocalcin-driven gene therapy have been conducted to treat hormone refractory metastatic tumors, detailed mechanisms controlling osteocalcin expression needs to be clarified. We aim to learn how osteocalcin expression is...


Source: Cancer Weekly (2009-05-19)

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