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Cancer Weekly

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Immunotherapy



Investigators at Kumamoto University publish new data on immunotherapy



May 26th, 2009

"Numerous tumor-associated antigens (TAA) have been identified and their use in immunotherapy is considered to be promising. For TAA-based immunotherapy to be broadly applied as standard anticancer medicine. methods for active immunization should be improved," researchers in Honjo, Japan report.

"In the present Study, we demonstrated the efficacy of multiple TAA-targeted dendritic cell (DC) vaccines and also the additive effects of loading alpha-galactosylceramide to DC using mouse melanoma models. Oil the basis of previously established methods to generate DC from mouse embryonic stein cells (ES-DC). 4 kinds of genetically modified ES-DC, which expressed the...


Source: Cancer Weekly (2009-05-26)

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