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Cancer Weekly

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Adenocarcinoma



Studies from University of Alabama add new findings in the area of adenocarcinoma



May 26th, 2009

According to recent research from the United States, "Several studies have examined the prognostic value of the codon 72 polymorphism of the p53 gene in colorectal adenocarcinoma, but none have addressed patient race/ethnicity. Therefore, this study assessed the prognostic value of this polymorphism in African American and Caucasian colorectal adenocarcinoma patients separately."

"Colorectal adenocarcinomas from 137 African Americans and 236 non-Hispanic Caucasians were assessed for p53 mutations and genotyped for the codon 72 polymorphism. The phenotypes were correlated with p53 mutational status, clinicopathologic features, and patient survival using the X 2 test and...


Source: Cancer Weekly (2009-05-26)

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