Cancer Gene Therapy
Data on cancer gene therapy published by J.A. Westwood and colleagues
Published in Cancer Weekly, May 26th, 2009
"In this study we aimed to determine the suitability of the Lewis-Y carbohydrate antigen as a target for immunotherapy using genetically redirected T cells, Using the 3S193 monoclonal antibody and immunohistochemistry, Lewis-Y was found to be expressed on a range of tumors including 42% squamous cell lung carcinoma, 80% lung adenocarcinoma. 25% ovarian carcinoma, and 25% colorectal adenocarcinoma. Expression levels varied from low to intense on between 1% and 90% of tumor cells," scientists writing in the Journal of Immunotherapy report.
"Lewis-(Y) was also found in soluble form in sera from both normal donors and cancer patients using a newly developed...
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Source: Cancer Weekly (2009-05-26)
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