Cancer Weekly
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Cancer Gene Therapy
Data on cancer gene therapy discussed by researchers at University of Alabama, Gene Therapy Center
June 2nd, 2009
A report, 'Armed replicating adenoviruses for cancer virotherapy,' is newly published data in Cancer Gene Therapy. According to a study from the United States, "Conditionally replicating adenoviruses (CRAds) have many advantages as agents for cancer virotherapy and have been safely used in human clinical trials. However, replicating adenoviruses have been limited in their ability to eliminate tumors by oncolysis." "Thus, the efficacy of these agents must be improved. To this end, CRAds have been engineered to express therapeutic transgenes that exert antitumor effects independent of direct viral oncolysis. These transgenes can be expressed under native gene...
Source: Cancer Weekly (2009-06-02)
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