Contact Dermatitis

Research findings from M.R.A. Hussein et al update understanding of contact dermatitis

Published in Cancer Weekly, June 2nd, 2009

"Allergic contact dermatitis (ACD) is a cell-mediated, delayed type IV immunologic reaction. Atopic dermatitis (AD) is a chronic inflammatory skin disease that results from a complex interaction between immunologic, genetic, and environmental factors," researchers in Abha, Saudi Arabia report.

"Pityriasis rosea (PR) is a self-limited eruption of unknown etiology. Immune cell infiltrate is a constant feature in the inflammatory skin diseases. Here, we performed phenotypical characterization of the immune cells in ACD, AD and PR (ten cases each). We performed immunohistochemical stains for B cells (CD20), T cells (CD3), histiocytes (CD68) and T cells with cytotoxic...

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Source: Cancer Weekly (2009-06-02)

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