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Cancer Weekly

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Cancer Gene Therapy



Data on cancer gene therapy reported by researchers at Academic Medical Center



June 2nd, 2009

Fresh data on cancer gene therapy are presented in the report 'Allele-specific cancer cell killing in vitro and in vivo targeting a single-nucleotide polymorphism in POLR2A.' "Cancer is one of the diseases for which RNA interference is a potential therapeutic approach. Genes involved in the promotion or maintenance of tumor growth are obvious targets for RNAi," researchers in Amsterdam, Netherlands report.

"RNAi is also considered an attractive additional approach to conventional chemotherapy for cancer treatment. Moreover, siRNAs have shown a high specificity for their molecular target mRNAs as they can selectively inhibit cancer-promoting genes that differ by a point...


Source: Cancer Weekly (2009-06-02)

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