Cancer Weekly
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Cancer Gene Therapy
Researchers at National Cancer Center Research Institute release new data on cancer gene therapy
June 2nd, 2009
Fresh data on cancer gene therapy are presented in the report 'Oncolytic virus therapy for pancreatic cancer using the adenovirus library displaying random peptides on the fiber knob.' "A conditionally replicative adenovirus is a novel anticancer agent designed to replicate selectively in tumor cells. However, a leak of the virus into systemic circulation from the tumors often causes ectopic infection of various organs," scientists in Tokyo, Japan report. "Therefore, suppression of naive viral tropism and addition of tumor-targeting potential are necessary to secure patient safety and increase the therapeutic effect of an oncolytic adenovirus in the clinical setting. We...
Source: Cancer Weekly (2009-06-02)
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