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Reports summarize life sciences research from K. Kang and co-authors

Published in Cancer Weekly, June 2nd, 2009

"Phytoestrogens are the natural compounds isolated from plants, which are structurally similar to animal estrogen, 17 beta-estradiol. Tectoridin, a major isoflavone isolated from the rhizome of Belamcanda chinensis," investigators in South Korea report.

"Tectoridin is known as a phytoestrogen, however, the molecular mechanisms underlying its estrogenic effect are remained unclear. In this study we investigated the estrogenic signaling triggered by tectoridin as compared to a famous phytoestrogen, genistein in MCF-7 human breast cancer cells. Tectoridin scarcely binds to ER alpha as compared to 17 beta-estradiol and genistein. Despite poor binding to ER alpha, tectoridin...

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