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Osteosarcoma

Findings in osteosarcoma reported from Kyung-Hee University

Published in Cancer Weekly, June 2nd, 2009

"Aims and background. Ezrin is a membrane-cytoskeleton linker protein involved in regulation of the growth and metastatic behavior of cancer cells," researchers in Seoul, South Korea report.

"Metastatic tumor antigen (MTA) is a potential metastasis-associated protein. The objective of this study was to evaluate the expression of ezrin and MTA and their correlation with clinicopathological features in osteosarcomas of the jaw. We analyzed ezrin and MTA protein levels by immunohistochemistry in 31 osteosarcomas of the jaw. The mean age at diagnosis was 39 years and half of the patients were male. The mandible (n = 19) was more frequently involved than the maxilla (n =...

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