Bladder Cancer Genetics
Studies from J.P. Grando et al provide new data on bladder cancer genetics
Published in Cancer Weekly, June 2nd, 2009
Investigators publish new data in the report 'Association between polymorphisms in the biometabolism genes CYP1A1, GSTM1, GSTT1 and GSTP1 in bladder cancer.' According to recent research from Londrina, Brazil, "Numerous enzymes, including Cytochrome P450s (phase I) and Glutathione-S-transferases (phase II), are involved in the metabolic activation and detoxification of carcinogens. Epidemiological studies have consistently demonstrated that bladder cancer is strongly associated with cigarette smoking, and the risk for the development of this neoplasia may be modified by individual differences in carcinogen-metabolizing genes."
"We investigated the relationship between...
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Source: Cancer Weekly (2009-06-02)
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