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Cancer Weekly

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Angiogenesis



Study results from H. Kobayashi and colleagues in the area of angiogenesis published



June 2nd, 2009

"Several new drugs that are targeted towards various angiogenic factors have shown considerable potential for controlling tumor proliferation and metastases. Expression levels of the targeted genes in primary tumors and metastases should be understood to maximize the use of such drugs," scientists in Tokyo, Japan report.

"The present study aimed to clarify associations between mRNA levels of cyclooxygenase 2 (COX-2) and angiogenic factors [vascular endothelial growth factor (VEGF) and interleukin-8 (IL-8)] in primary colorectal cancer and in corresponding liver metastasis. We also compared these gene expressions of primary colorectal cancer between patients with and...


Source: Cancer Weekly (2009-06-02)

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