Cancer Weekly
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Apoptosis
New apoptosis data have been reported by X.Y. Chen and co-authors
June 2nd, 2009
According to recent research from Beijing, People's Republic of China, "Cardiotoxin III (CTX III), a 60-amino acid basic polypeptide isolated from Naja venom, showed potential therapeutic activity toward cancer cells. Here we report that CTX III inhibited proliferation of human leukemia K562 cells by G2/M phase arresting and apoptosis which was associated with the activation of caspase-8 and cytochrome c release as well as the p38 and c-Jun N-terminal protein kinase (JNK) phosphorylation signaling pathway." "We further demonstrated that daily administration of CTX III for 2 d to chicken chorioallantoic membrane (CAM) bearing tumours derived from the CAM at E10...
Source: Cancer Weekly (2009-06-02)
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