Cancer Weekly
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Apoptosis
Study results from L. Li and colleagues update understanding of apoptosis
June 2nd, 2009
According to recent research from Kimiidera, Japan, "Although death-associated protein kinase (DAPK) is a Ca2+/calmodulin-regulated serine/threonine kinase that plays important roles in various types of apoptotic cell death, there have been no reports of its tissue distributions and functions in female reproductive organs. By comparing C57BL/6 wild-type mice with DAPK-mutant mice lacking the 74-amino acid catalytic kinase domain of DAPK, the cellular distributions and biological functions of DAPK in murine ovaries were investigated." "In situ hybridization analyses with sense and antisense riboprobes revealed that DAPK mRNA was selectively and highly expressed in...
Source: Cancer Weekly (2009-06-02)
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