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Non-Hodgkin Lymphoma Prognosis

Study data from S. Szvalb et al provide new insights into non-hodgkin lymphoma prognosis

Published in Cancer Weekly, June 2nd, 2009

New research, 'Lack of HER-2 gene amplification in non-Hodgkin lymphoma using chromogenic in situ hybridisation test,' is the subject of a report. "HER-2 is overexpressed in 25% of breast cancers and provides a poor prognostic factor, affecting treatment decisions including administration of trastuzumab. Single reports show a lack of HER-2 in non-Hodgkin lymphomas (NHLs) using immunohistochemical (IHC) test," researchers in Israel report.

"The present study evaluates HER-2 in NHLs using the chromogenic in situ hybridisation (CISH) test, which is more accurate than IHC, to seek new prognostic factors. The secondary aim of the study is to investigate efficacy of using...

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