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Signature Genomic Laboratories



Signature Genomic Laboratories Detects Chromosome Abnormalities in Individuals with Genetic Disorders Associated with Susceptibility to Cancer



June 9th, 2009

Geneticists at Signature Genomic Laboratories recently demonstrated that microarray-based genetic testing can identify chromosome abnormalities that cause genetic disorders associated with susceptibility to cancer prior to the onset of symptoms.

In their study, published in the May issue of Genetics in Medicine, geneticists from Signature reviewed data from 18,437 individuals who were tested by microarray analysis for unexplained mental retardation and congenital anomalies. DNA copy number gains or losses that encompassed gene regions associated with recognized genetic conditions with an increased risk for cancer were identified in 34 individuals. Almost three-quarters...


Source: Cancer Weekly (2009-06-09)

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