Cell Proliferation
Studies from A.T. Hbibi et al in the area of cell proliferation described
Published in Cancer Weekly, June 9th, 2009
"The signal transducers and activators of transcription (STATs) convey signals from the membrane to the nucleus in response to cytokines or growth factors. STAT3 is activated in response to cytokines involved mostly in cell proliferation; STAT1 is activated by cytokines, including interferon-gamma, involved in defence against pathogens and the inhibition of cell proliferation," investigators in Bobigny, France report.
"STAT3, which is frequently activated in tumour cells, is a valuable target with respect to achieving inhibition of tumour cell proliferation. Indeed, its inhibition results in cell death. We previously observed that inhibition of the transcription factor...
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Source: Cancer Weekly (2009-06-09)
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