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Cancer Weekly

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Bone Research



Findings from University of Toronto advance knowledge in bone research



June 9th, 2009

"Pain flare occurs in over one-third of patients receiving palliative radiotherapy for bone metastases. A single dose of dexamethasone can decrease the incidence of pain flare during the first 2 days immediately after radiotherapy," scientists in Toronto, Canada report.

"We conducted a phase 11 prospective study to investigate the prophylactic role of prolonged dexamethasone. Patients with bone metastases treated with a single 8Gy were prescribed 8mg dexamethasone just before palliative radiotherapy and for 3 consecutive days after treatment. Worst pain score and analgesic consumption data were collected at baseline and daily for 10 days after treatment. Analgesic...


Source: Cancer Weekly (2009-06-09)

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