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Carcinoma
Study data from A.C. Bertagnolli and co-authors update knowledge of carcinoma
June 16th, 2009
"The immunohistochemical expression of p63, Delta Np63, and p53 was studied in mixed tumors of canine mammary glands (13 benign mixed tumors and 19 carcinomas arising from benign mixed tumors) to determine the role of p63 and its isoform Delta Np63 in the development of mixed tumors, as well as to assess its relation with p53. P63 was expressed in myoepithelial cells of all benign mixed tumors and in 18 of 19 carcinomas in mixed tumors," scientists in Belo Horizonte, Brazil report. "The p63-negative carcinoma in mixed tumors was invasive, and a loss of p63 was detected in the other malignant tumors showing a discontinuous p63-stained myoepithelial layer. Delta Np63 was...
Source: Cancer Weekly (2009-06-16)
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