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Cancer Gene Therapy
HungKuang University, College of Medicine details research in cancer gene therapy
June 16th, 2009
A report, 'Immunotherapy: rAAV2 expressing interleukin-15 inhibits HeLa cell tumor growth in mice,' is newly published data in Journal of Biomedical Science. "Human interleukin-15 (hIL15) has anti-tumor activities, but it is not convenient for tumor treatment because of its short half-life. A gene therapy for mouse lung cancer using an adenovirus vector expressing IL15 has been reported," researchers in Taichung, Taiwan report. "However, adenovirus vector-mediated gene therapy can provoke cellular toxicity and inflammatory reactions. The recombinant adenovirus-associated vector 2 (rAAV2) is safer due to minimal cellular toxicity and immune response. In order to...
Source: Cancer Weekly (2009-06-16)
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