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Acute Myeloid Leukemia
Reports from University of Bergen highlight recent research in acute myeloid leukemia
June 16th, 2009
According to a study from Bergen, Norway, "The molecular changes in vivo in acute myeloid leukemia cells early after start of conventional genotoxic chemotherapy are incompletely understood, and it is not known if early molecular modulations reflect clinical response. The gene expression was examined by whole genome 44 k oligo microarrays and 12 k cDNA microarrays in peripheral blood leukocytes collected from seven leukemia patients before treatment, 2-4 h and 18-24 h after start of chemotherapy and validated by real-time quantitative PCR." "Statistically significantly upregulated genes were classified using gene ontology (GO) terms. Parallel samples were examined by...
Source: Cancer Weekly (2009-06-16)
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