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Cancer Weekly

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Acute Myeloid Leukemia



Reports from Y. Kobayashi et al highlight recent research in acute myeloid leukemia



June 16th, 2009

According to recent research published in the International Journal of Hematology, "The primary objective of this study was to investigate the tolerability, efficacy and pharmacokinetic profile of gemtuzumab ozogamicin (GO) in patients with relapsed and/or refractory CD33-positive acute myeloid leukemia (AML). Patients received 2-h infusions of GO twice with an interval of approximately 14 days."

"Tolerability was assessed using the National Cancer Institute Common Toxicity Criteria Version 2.0. Samples for pharmacokinetics were taken on day 1 and day 8 of the first treatment cycle. The dose was increased stepwise and, in each cohort, patients were treated at the...


Source: Cancer Weekly (2009-06-16)

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