Cancer Weekly
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Adenocarcinoma
Data on adenocarcinoma discussed by M. Miyazawa and colleagues
June 16th, 2009
According to recent research from Hidaka, Japan, "Hypoxia-inducible factor-1 (HIF-1) is an essential transcription factor that mediates cellular and systemic homeostatic responses to reduced oxygen availability in mammals. So far, using immunohistochemistry we have analyzed the association of HIF-1 alpha expression with histological type among epithelial ovarian tumors." "In the present study, quantitative analyses of activated HIF-1 level in the nucleus and of accumulated HIF-1 alpha level in the cytoplasm were performed to clarify whether or not the hypoxic state would be correlated to histology, malignancy, and tumor size in epithelial ovarian tumors. HIF-1 level in...
Source: Cancer Weekly (2009-06-16)
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