Cancer Weekly
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Adenocarcinoma
Research on adenocarcinoma discussed by scientists at University of Regensburg
June 16th, 2009
According to recent research published in the American Journal of Surgical Pathology, "The prevalence and development of microsatellite instability (MSI) and underlying mismatch repair (MMR) deficiency in the carcinogenesis of adenocarcinomas of the papilla of Vater and their precursor lesions are not Well established. We analyzed 120 ampullary adenomas (31 pure adenomas and 89 carcinoma-associated adenomas) and 170 pure adenocarcinomas for MSI, immunohistochemical expression of MMR proteins and specific histopathologic features.The most common histologic subtype was intestinal (46.5%), followed by pancreatobiliary (23.5%), poorly differentiated adenocarcinomas (12.9%),...
Source: Cancer Weekly (2009-06-16)
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