Cancer Weekly
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Angiogenesis
Studies from Tongji University further understanding of angiogenesis
June 16th, 2009
According to recent research from Shanghai, People's Republic of China, "As one of the blood-rich malignancies, the growth and metastasis of osteosarcoma both depend on its angiogenesis, a procedure in which vascular endothelial growth factor (VEGF) acts essentially. Although with the advent of neoadjuvant chemotherapy, more aggressive surgical excision and logical therapy strategy, the 5-year survival rate remains relatively stable at 70%, at best." "However, antiangiogenic therapeutics, through gene silencing and targeting key sequences, probably brings an outlook to the conventional algorithm. In our current research, human-specific VEGF-siRNA (small interfering RNA)...
Source: Cancer Weekly (2009-06-16)
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