Cancer Weekly
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Angiogenesis
Research from X.A. Ren and co-researchers in the area of angiogenesis described
June 16th, 2009
According to recent research published in the British Journal of Pharmacology, "The critical role of blood supply in the growth of solid tumours makes blood vessels an ideal target for anti-tumour drug discovery. The anti-angiogenic and vascular disrupting activities of C9, a newly synthesized microtubule-depolymerizing agent, were investigated with several in vitro and in vivo models." "Possible mechanisms involved in its activity were also assessed. Microtubule-depolymerizing actions were assessed by surface plasmon resonance binding, competitive inhibition and cytoskeleton immunofluorescence. Anti-angiogenic and vascular disrupting activities were tested on...
Source: Cancer Weekly (2009-06-16)
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