Cancer Therapy
Research on cancer therapy detailed by J. Shen and co-authors
Published in Cancer Weekly, June 16th, 2009
Researchers detail in 'Development of a fully human anti-PDGFRbeta antibody that suppresses growth of human tumor xenografts and enhances antitumor activity of an anti-VEGFR2 antibody,' new data in cancer. "Platelet-derived growth factor receptor beta (PDGFRbeta) is upregulated in most of solid tumors. It is expressed by pericytes/smooth muscle cells, fibroblast, macrophage, and certain tumor cells," scientists in the United States report.
"Several PDGF receptor-related antagonists are being developed as potential antitumor agents and have demonstrated promising antitumor activity in both preclinical and clinical settings. Here, we produced a fully human neutralizing...
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Source: Cancer Weekly (2009-06-16)
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