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Cancer Gene Therapy
Research on cancer gene therapy discussed by scientists at University of Guelph, Department of Biomedical Sciences
June 23rd, 2009
Investigators publish new data in the report 'Reversibility and recurrence of IGF-IR-induced mammary tumors.' According to recent research from Guelph, Canada, "The type-I insulin-like growth factor receptor (IGF-IR) is frequently overexpressed in breast cancer and therapeutic agents targeting IGF-IR are currently in development. The ultimate success of anti-IGF-IR therapies will depend on the extent to which established tumors remain dependent upon IGF-IR signaling for sustained growth." "To investigate the potential benefits and pitfalls of targeting IGF-IR, we used a doxycycline inducible mouse model of IGF-IR initiated breast cancer. We found that downregulation of...
Source: Cancer Weekly (2009-06-23)
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