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Acute Lymphoblastic Leukemia
Findings from Seoul National University broaden understanding of acute lymphoblastic leukemia
June 23rd, 2009
"Relapse is the major cause of treatment failure in acute lymphoblastic leukemia (ALL), yet there is no established treatment for relapsed ALL. To improve the induction remission rate, we modified the dose of idarubicin in the original Children's Cancer Group (CCG)-1884 protocol, and retrospectively compared the results," scientists in Seoul, South Korea report. "Twenty-eight patients diagnosed with relapsed ALL received induction chemotherapy according to the CCG-1884 protocol. Complete remission (CR) rate in all patients after induction chemotherapy was 57%. The idarubicin 10 mg/m(2)/week group showed CR rate of 74%, compared with the 22% CR rate of the idarubicin...
Source: Cancer Weekly (2009-06-23)
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