Colon Cancer
Research in the area of colon cancer reported from Eulji University, Medical Department
Published in Cancer Weekly, June 23rd, 2009
According to recent research from South Korea, "Hereditary non-polyposis colorectal cancer (HNPCC) is an inherited disease caused by a germline mutation of the mismatch repair (MMR) genes, and the distinctive feature is that colorectal and extracolonic malignancies occur early in life. We report on the case of a Korean HNPCC family with endometrial cancer, with the goal of elucidating the involvement of an MMR deficiency."
"Although the family history did not fulfill the Amsterdam criteria II, blood samples were subjected to genetic testing by the revised Bethesda guidelines. Immunohistochemistry and direct sequencing of the genomic DNA identified a C insertion at the...
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Source: Cancer Weekly (2009-06-23)
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