Cancer Weekly
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Bladder Cancer
Reports summarize bladder cancer research from University of Michigan
June 23rd, 2009
According to recent research published in the journal Cancer Research, "In bladder cancer, clinical grade and stage fail to capture outcome. We developed a clinically applicable quantitative PCR (QPCR) gene signature to predict progression in nonmuscle-invasive bladder cancer." "Comparative metaprofiling of 12 DNA microarray data sets (comprising 631 samples and 241,298 probe sets) identified 96 genes, which showed differential expression in seven clinical outcome categories, or were identified as outliers, historic markers, or housekeeping genes. QPCR was done to determine mRNA expression from 96 bladder tumors. Fifty-seven genes differentiated T2 from non-T2...
Source: Cancer Weekly (2009-06-23)
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