Bladder Cancer

Scientists at Istanbul University report research in bladder cancer

Published in Cancer Weekly, June 23rd, 2009

"Carcinogenic molecules from cigarettes are known to cause DNA damage to bladder epithelial cells, but such damage can be corrected by some DNA repair mechanisms such as base and nucleotide excision repair, double-strand repair and mismatch repair. Various gene products play a role in these DNA repair systems," scientists writing in the journal Anticancer Research report.

"The aim of this study was to investigate six of these genes (XRCC1, XRCC3, XPD, XPG, APE1, hOGG1) each of which has a separate role in these repair mechanisms. The study was performed on 83 bladder cancer patients and 45 health), controls. The genes were amplified by polymerase chain reaction...

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Source: Cancer Weekly (2009-06-23)

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