Cancer Vaccines

Data on cancer vaccines published by researchers at National Cancer Institute

Published in Cancer Weekly, June 23rd, 2009

"The tumor-associated Tn antigen has been investigated extensively as a biomarker and therapeutic target. Cancer vaccines containing the Tin antigen as a single tumor antigen or as a component of a polyvalent vaccine have progressed into phase I and II clinical trials," scientists in the United States report.

"One major focus of Tn-based vaccines is the treatment of prostate cancer patients. Although expression of the antigen on prostate tumors is a critical prerequisite, previous reports investigating Tn expression in prostate tumors have produced conflicting results. Using a combination of immunohistochemistry and carbohydrate microarray profiling, we show that only...

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Source: Cancer Weekly (2009-06-23)

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