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Cancer Weekly

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Cancer Gene Therapy



Findings from Harvard University, Research Center provide new insights into cancer gene therapy



June 30th, 2009

Researchers detail in 'ATR-Chk1 pathway inhibition promotes apoptosis after UV treatment in primary human keratinocytes: potential basis for the UV protective effects of caffeine,' new data in cancer gene therapy. According to recent research from the United States, "New approaches to prevent and reverse UV damage are needed to combat rising sunlight-induced skin cancer rates. Mouse studies have shown that oral or topical caffeine promotes elimination of UV-damaged keratinocytes through apoptosis and markedly inhibits subsequent skin cancer development."

"This potentially important therapeutic effect has not been studied in human skin cells. Here, we use primary human...


Source: Cancer Weekly (2009-06-30)

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