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Cancer Gene Therapy
Researchers from University of Amsterdam, Department of Surgery publish findings in cancer gene therapy
June 30th, 2009
Scientists discuss in 'Fiber-chimeric adenoviruses expressing fibers from serotype 16 and 50 improve gene transfer to human pancreatic adenocarcinoma' new findings in cancer gene therapy. According to recent research from Amsterdam, Netherlands, "Survival of patients with pancreatic cancer is poor. Adenoviral (Ad) gene therapy employing the commonly used serotype 5 reveals limited transduction efficiency due to the low amount of coxsackie-adenovirus receptor on pancreatic cancer cells." "To identify fiber-chimeric adenoviruses with improved gene transfer, a library of Ad vectors based on Ad5 and carrying fiber molecules consisting of 16 other serotypes were transduced...
Source: Cancer Weekly (2009-06-30)
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