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Cancer Gene Therapy
Studies from University of Surrey, Department of Oncology further understanding of cancer gene therapy
June 30th, 2009
Investigators publish new data in the report 'Inhibition of the aquaporin 3 water channel increases the sensitivity of prostate cancer cells to cryotherapy.' "Aquaporins (AQPs) are intrinsic membrane proteins that facilitate selective water and small solute movement across the plasma membrane. In this study, we investigate the role of inhibiting AQPs in sensitising prostate cancer cells to cryotherapy," researchers in Guildford, the United Kingdom report. "PC-3 and DU145 prostate cancer cells were cooled to 0, -5 and -10 degrees C. The expression of AQP3 in response to freezing was determined using real-time quantitative polymerase chain reaction (RT-qPCR) and western...
Source: Cancer Weekly (2009-06-30)
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